Gene name:
CCL8 (MCP2;SCYA10;SCYA8) ;
Protein name:
C-C motif chemokine 8 ;
Alternative:
Monocyte chemoattractant protein 2 ;HC14 ;Small-inducible cytokine A8 ;Monocyte chemotactic protein 2 (MCP-2) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Monomer or homodimer; in equilibrium.
Function:
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKVSAALLCL | LLMAATFSPQ | GLAQPDSVSI | PITCCFNVIN | RKIPIQRLES |
99:
YTRITNIQCP | KEAVIFKTKR | GKEVCADPKE | RWVRDSMKHL | DQIFQNLKP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Dog
Bovine
Human
Mouse
Pig
ELISA Kit for Human C-C motif chemokine 8
ELISA Kit for Human C-C motif chemokine 8
ELISA Kit for Human C-C motif chemokine 8
ELISA Kit for Human C-C motif chemokine 8
ELISA Kit for Human C-C motif chemokine 8
CLIA Kit for Human C-C motif chemokine 8
CLIA Kit for Human C-C motif chemokine 8
CLIA Kit for Human C-C motif chemokine 8
CLIA Kit for Human C-C motif chemokine 8
CLIA Kit for Human C-C motif chemokine 8
Polyclonal Antibody for Human C-C motif chemokine 8
Polyclonal Antibody for Human C-C motif chemokine 8
Polyclonal Antibody for Human C-C motif chemokine 8
Polyclonal Antibody for Human C-C motif chemokine 8
Polyclonal Antibody for Human C-C motif chemokine 8
Monoclonal Antibody for Human C-C motif chemokine 8
Monoclonal Antibody for Human C-C motif chemokine 8
Monoclonal Antibody for Human C-C motif chemokine 8
Monoclonal Antibody for Human C-C motif chemokine 8
Monoclonal Antibody for Human C-C motif chemokine 8
Protein for Human C-C motif chemokine 8
Protein for Human C-C motif chemokine 8
Protein for Human C-C motif chemokine 8
Protein for Human C-C motif chemokine 8
Protein for Human C-C motif chemokine 8
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"The human MCP-2 gene (SCYA8): cloning, sequence analysis, tissue expression, and assignment to the CC chemokine gene contig on chromosome 17q11.2."
van Coillie E.
,
Fiten P.
,
Nomiyama H.
,
Sakaki Y.
,
Miura R.
,
Yoshie O.
,
van Damme J.
,
Opdenakker G.
Genomics40:323-331(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLN-69
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLN-69
tissue :
Bone marrow .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLN-69
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 23-99
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 26-99
tissue :
Osteosarcoma .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION OF MCP-2(6-76);IDENTIFICATION BY MASS SPECTROMETRY;PROTEOLYTIC PROCESSING OF N-TERMINAL;FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 24-99;PYROGLUTAMATE FORMATION AT GLN-24;DISULFIDE BONDS